Gene
mhc2daa
- ID
- ZDB-GENE-980526-201
- Name
- major histocompatibility complex class II DAA gene
- Symbol
- mhc2daa Nomenclature History
- Previous Names
-
- DAA
- mhc2a
- mhc2d8.37a3 (1)
- mhcdaa
- a4
- fj17g12
- si:busm1-266f07.2
- si:dz266f07.2
- si:zfos-2070c2.4
- wu:fa93a04
- wu:fj17g12
- zgc:103599
- zgc:113853
- zgc:113912
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable MHC class II protein complex binding activity and peptide antigen binding activity. Predicted to be involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of T cell activation. Predicted to act upstream of or within adaptive immune response and antigen processing and presentation of peptide or polysaccharide antigen via MHC class II. Predicted to be located in membrane. Predicted to be part of MHC class II protein complex. Predicted to be active in late endosome membrane and lysosomal membrane.
- Genome Resources
- Note
-
novel MHCII alpha chain protein
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Domain | IPR001003 | MHC class II, alpha chain, N-terminal |
| Domain | IPR003597 | Immunoglobulin C1-set |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Family | IPR050160 | Major Histocompatibility Complex/Immunoglobulin |
| Homologous_superfamily | IPR011162 | MHC classes I/II-like antigen recognition protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014745 | MHC class II, alpha/beta chain, N-terminal |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Major Histocompatibility Complex/Immunoglobulin | MHC classes I/II-like antigen recognition protein | MHC class II, alpha/beta chain, N-terminal | MHC class II, alpha chain, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q1MTC7
|
236 | |||||||||
|
UniProtKB:Q4KM20
|
236 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA | si:busm1-266f07.2-001 (1) | Havana | 2,111 nt | ||
| mRNA |
si:busm1-266f07.2-201
(1)
|
Ensembl | 1,590 nt |
Interactions and Pathways
No data available
Plasmids
No data available