Gene
ddx3xb
- ID
- ZDB-GENE-980526-150
- Name
- DEAD-box helicase 3 X-linked b
- Symbol
- ddx3xb Nomenclature History
- Previous Names
-
- ddx3b
- etID309900.24 (1)
- p110a
- pl10
- pl10a
- wu:fb43h11
- wu:fy72b06
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity and RNA helicase activity. Involved in brain development. Predicted to localize to P granule and nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human DDX3X (DEAD-box helicase 3 X-linked).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Fitzgerald et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, X-linked syndromic, Snijders Blok type | 300958 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000629 | ATP-dependent RNA helicase DEAD-box, conserved site |
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR011545 | DEAD/DEAH box helicase domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR014014 | RNA helicase, DEAD-box type, Q motif |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | ATP-dependent RNA helicase DEAD-box, conserved site | DEAD/DEAH box helicase domain | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | RNA helicase, DEAD-box type, Q motif |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BGM7
|
705 | ||||||
|
UniProtKB:Q6PBB2
|
688 | ||||||
|
UniProtKB:A0A8M2BG33
|
719 | ||||||
|
UniProtKB:A0A8M2BG39
|
702 | ||||||
|
UniProtKB:A0A8M2BG28
|
704 | ||||||
|
UniProtKB:A0A8M2BG36
|
721 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ddx3xb-201
(1)
|
Ensembl | 4,367 nt | ||
| mRNA |
ddx3xb-203
(1)
|
Ensembl | 886 nt | ||
| mRNA |
ddx3xb-204
(1)
|
Ensembl | 1,070 nt | ||
| ncRNA |
ddx3b-004
(1)
|
Ensembl | 640 nt | ||
| ncRNA |
ddx3b-005
(1)
|
Ensembl | 949 nt | ||
| ncRNA |
ddx3b-006
(1)
|
Ensembl | 632 nt | ||
| ncRNA |
ddx3b-007
(1)
|
Ensembl | 788 nt |
Interactions and Pathways
No data available
Plasmids
No data available