Gene
her6
- ID
- ZDB-GENE-980526-144
- Name
- hairy-related 6
- Symbol
- her6 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in Notch signaling pathway; nervous system development; and somite specification. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; mesoderm; nervous system; neuronal stem cell; and pectoral fin. Orthologous to human HES1 (hes family bHLH transcription factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 61 figures from 44 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb129 (41 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Coolen et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Hairy and Enhancer of Split/HEY-related | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Orange domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6PBX3
|
270 |
Interactions and Pathways
No data available
Plasmids