Gene
lhx1b
- ID
- ZDB-GENE-980526-116
- Name
- LIM homeobox 1b
- Symbol
- lhx1b Nomenclature History
- Previous Names
-
- lim6 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in blastoderm; central nervous system; margin; midbrain neural keel; and shield. Orthologous to human LHX1 (LIM homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017970 | Homeobox, conserved site |
| Domain | IPR001356 | Homeodomain |
| Domain | IPR001781 | Zinc finger, LIM-type |
| Domain | IPR049618 | Lhx1/5, LIM domain 1 |
| Domain | IPR049619 | Lhx1/5, LIM domain 2 |
| Family | IPR050453 | LIM/homeobox transcription factors |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Lhx1/5, LIM domain 1 | Lhx1/5, LIM domain 2 | LIM/homeobox transcription factors | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:O13106
|
402 |
Interactions and Pathways
No data available
Plasmids