Gene
kcna1b
- ID
- ZDB-GENE-140515-1
- Name
- potassium voltage-gated channel, shaker-related subfamily, member 1b
- Symbol
- kcna1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport; protein homooligomerization; and regulation of ion transmembrane transport. Predicted to localize to voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in episodic ataxia type 1. Is expressed in brain; heart; and testis. Orthologous to human KCNA1 (potassium voltage-gated channel subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| episodic ataxia type 1 | Alliance | Episodic ataxia/myokymia syndrome | 160120 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Domain | IPR003131 | Potassium channel tetramerisation-type BTB domain |
| Domain | IPR005821 | Ion transport domain |
| Family | IPR003968 | Potassium channel, voltage dependent, Kv |
| Family | IPR003972 | Potassium channel, voltage dependent, Kv1 |
| Family | IPR004048 | Potassium channel, voltage dependent, Kv1.1 |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | Ion transport domain | Potassium channel tetramerisation-type BTB domain | Potassium channel, voltage dependent, Kv | Potassium channel, voltage dependent, Kv1 | Potassium channel, voltage dependent, Kv1.1 | SKP1/BTB/POZ domain superfamily | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FEJ3
|
493 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcna1b-201
(1)
|
Ensembl | 1,482 nt | ||
| mRNA |
kcna1b-202
(1)
|
Ensembl | 2,075 nt |
Interactions and Pathways
No data available
Plasmids
No data available