Gene
adgrg2a
- ID
- ZDB-GENE-140106-206
- Name
- adhesion G protein-coupled receptor G2a
- Symbol
- adgrg2a Nomenclature History
- Previous Names
-
- gpr64
- gpr64a
- zmp:0000001246 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in male reproductive system disease. Is expressed in several structures, including eye; heart; integument; muscle; and pleuroperitoneal region. Orthologous to human ADGRG2 (adhesion G protein-coupled receptor G2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Harty et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked congenital bilateral absence of vas deferens | Alliance | Congenital bilateral absence of vas deferens, X-linked | 300985 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR000203 | GPS motif |
| Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
| Domain | IPR017452 | GPCR, rhodopsin-like, 7TM |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Homologous_superfamily | IPR046338 | GAIN domain superfamily |
Domain Details Per Protein
| Protein | Length | GAIN domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | GPCR, rhodopsin-like, 7TM | GPS motif |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F4F2
|
947 | ||||||
|
UniProtKB:A0A8M2B9R8
|
2289 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance