Gene
pgfb
- ID
- ZDB-GENE-131127-445
- Name
- placental growth factor b
- Symbol
- pgfb Nomenclature History
- Previous Names
-
- si:dkey-204k5.1
- zmp:0000000808
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have chemoattractant activity; growth factor activity; and vascular endothelial growth factor receptor binding activity. Predicted to be involved in several processes, including positive regulation of chemotaxis; positive regulation of endothelial cell proliferation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in asthma; brain disease (multiple); diabetic neuropathy; myocardial infarction; and pancreatic endocrine carcinoma. Orthologous to human PGF (placental growth factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived/Vascular endothelial growth factor |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PCW7
|
158 | |||
|
UniProtKB:X1WBL7
|
164 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance