Gene

terf2ip

ID
ZDB-GENE-131121-641
Name
telomeric repeat binding factor 2, interacting protein
Symbol
terf2ip Nomenclature History
Previous Names
  • RAP1 (1)
  • zmp:0000000584
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have telomeric DNA binding activity. Predicted to be involved in positive regulation of I-kappaB kinase/NF-kappaB signaling; regulation of nucleobase-containing compound metabolic process; and telomere maintenance via telomere lengthening. Predicted to localize to cytoplasm and shelterin complex. Is expressed in several structures, including gill; heart; liver; pleuroperitoneal region; and post-vent region. Orthologous to human TERF2IP (TERF2 interacting protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Wagner et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With terf2ip Human Ortholog
No data available
Associated With terf2ip Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001357 BRCT domain
Domain IPR015010 TERF2-interacting telomeric protein 1, Myb domain
Domain IPR021661 TRF2-interacting telomeric protein/Rap1, C-terminal
Family IPR039595 TE2IP/Rap1
Homologous_superfamily IPR009057 Homedomain-like superfamily
Homologous_superfamily IPR036420 BRCT domain superfamily
Homologous_superfamily IPR038104 TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily
Domain Details Per Protein
Protein Length BRCT domain BRCT domain superfamily Homedomain-like superfamily TE2IP/Rap1 TERF2-interacting telomeric protein 1, Myb domain TRF2-interacting telomeric protein/Rap1, C-terminal TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily
UniProtKB:A0A8M3B5S4 610
UniProtKB:Q6NYJ3 616
UniProtKB:A0A8M1P1Q7 616
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA terf2ip-201 (1) Ensembl 1,725 nt
mRNA terf2ip-202 (1) Ensembl 2,481 nt
mRNA terf2ip-203 (1) Ensembl 2,565 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations