Gene
pecam1a
- ID
- ZDB-GENE-130530-689
- Name
- platelet and endothelial cell adhesion molecule 1a
- Symbol
- pecam1a Nomenclature History
- Previous Names
-
- CD31 (1)
- pecam1
- zmp:0000000686
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway; cell-cell adhesion via plasma-membrane adhesion molecules; and immune response. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in midbrain hindbrain boundary and pharyngeal arch. Human ortholog(s) of this gene implicated in coronary artery disease; coronary stenosis; myocardial infarction; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Fowler et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Family | IPR050488 | Immunoglobulin Fc region receptor |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Immunoglobulin domain subtype | Immunoglobulin Fc region receptor | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R1B9
|
738 | ||||||
|
UniProtKB:A0A8M9PWY1
|
723 | ||||||
|
UniProtKB:A0JMH1
|
746 | ||||||
|
UniProtKB:A0A8M1NHB4
|
737 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pecam1a-201
(1)
|
Ensembl | 5,360 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance