Gene
dtx1
- ID
- ZDB-GENE-130503-1
- Name
- deltex 1, E3 ubiquitin ligase
- Symbol
- dtx1 Nomenclature History
- Previous Names
-
- zmp:0000001121
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to enable transferase activity and zinc ion binding activity. Acts upstream of with a negative effect on Notch signaling pathway. Acts upstream of or within glial cell differentiation and neuron differentiation. Predicted to be located in cytoplasm. Is expressed in nervous system and spinal cord neural tube. Orthologous to human DTX1 (deltex E3 ubiquitin ligase 1).
- Genome Resources
-
- Alliance (1)
- Gene:101885597 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Cheng et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Cheng et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR004170 | WWE domain |
| Domain | IPR018123 | WWE domain, subgroup |
| Domain | IPR018957 | Zinc finger, C3HC4 RING-type |
| Domain | IPR039396 | Deltex, C-terminal |
| Family | IPR039398 | Deltex family |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR037197 | WWE domain superfamily |
| Homologous_superfamily | IPR039399 | Deltex, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Deltex, C-terminal | Deltex, C-terminal domain superfamily | Deltex family | WWE domain | WWE domain, subgroup | WWE domain superfamily | Zinc finger, C3HC4 RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0U3RBN1
|
545 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance