Gene
cers3a
- ID
- ZDB-GENE-130320-1
- Name
- ceramide synthase 3a
- Symbol
- cers3a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity. Predicted to localize to integral component of membrane and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Is expressed in several structures, including digestive system; immature eye; intermediate cell mass of mesoderm; myotome; and pectoral fin. Orthologous to human CERS3 (ceramide synthase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Brondolin et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive congenital ichthyosis 9 | Alliance | Ichthyosis, congenital, autosomal recessive 9 | 615023 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeodomain | Sphingosine N-acyltransferase Lag1/Lac1-like | TRAM/LAG1/CLN8 homology domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q8A3
|
208 | ||||
|
UniProtKB:A0A8M9Q249
|
293 | ||||
|
UniProtKB:A0A140LFW4
|
380 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cers3a-201
(1)
|
Ensembl | 1,053 nt | ||
| mRNA |
cers3a-202
(1)
|
Ensembl | 4,937 nt | ||
| mRNA |
cers3a-203
(1)
|
Ensembl | 1,032 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance