Gene

ano1a

ID
ZDB-GENE-121127-3
Name
anoctamin 1, calcium activated chloride channel a
Symbol
ano1a Nomenclature History
Previous Names
  • ano1
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have protein dimerization activity. Predicted to be involved in cellular response to heat; chloride transmembrane transport; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in fast muscle cell and slow muscle cell. Orthologous to human ANO1 (anoctamin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Dayal et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ano1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Moyamoya disease 7 620687
?Intestinal dysmotility syndrome 620045
Associated With ano1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR032394 Anoctamin, dimerisation domain
Domain IPR049452 Anoctamin, transmembrane domain
Family IPR007632 Anoctamin
Domain Details Per Protein
Protein Length Anoctamin Anoctamin, dimerisation domain Anoctamin, transmembrane domain
UniProtKB:A0A8M3AUJ5 928
UniProtKB:A0A8M6Z1H3 924
UniProtKB:A0A8M1NT27 925
UniProtKB:A0A8M3BBA3 962
UniProtKB:A0A8M3AUL7 966
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations