Gene
kcna4
- ID
- ZDB-GENE-121127-2
- Name
- potassium voltage-gated channel, shaker-related subfamily, member 4
- Symbol
- kcna4 Nomenclature History
- Previous Names
-
- knca4
- zmp:0000001194
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have potassium ion binding activity and voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport; protein homooligomerization; and regulation of ion transmembrane transport. Predicted to localize to voltage-gated potassium channel complex. Orthologous to human KCNA4 (potassium voltage-gated channel subfamily A member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Gou et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Microcephaly, cataracts, impaired intellectual development, and dystonia with abnormal striatum | 618284 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000210 | BTB/POZ domain |
| Domain | IPR003131 | Potassium channel tetramerisation-type BTB domain |
| Domain | IPR005821 | Ion transport domain |
| Domain | IPR012897 | Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain |
| Family | IPR003968 | Potassium channel, voltage dependent, Kv |
| Family | IPR003972 | Potassium channel, voltage dependent, Kv1 |
| Family | IPR020467 | Potassium channel, voltage dependent, Kv1.4 |
| Homologous_superfamily | IPR011333 | SKP1/BTB/POZ domain superfamily |
| Homologous_superfamily | IPR027359 | Voltage-dependent channel domain superfamily |
| Homologous_superfamily | IPR037065 | Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain superfamily |
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | Ion transport domain | Potassium channel tetramerisation-type BTB domain | Potassium channel, voltage dependent, Kv | Potassium channel, voltage dependent, Kv1 | Potassium channel, voltage dependent, Kv1.4 | Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain | Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain superfamily | SKP1/BTB/POZ domain superfamily | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1Q929
|
667 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance