Gene

notum1a

ID
ZDB-GENE-120807-2
Name
notum, palmitoleoyl-protein carboxylesterase a
Symbol
notum1a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have palmitoleyl hydrolase activity. Involved in GPI anchor release; negative regulation of canonical Wnt signaling pathway; and regionalization. Predicted to localize to extracellular region. Is expressed in several structures, including axis; hindbrain neural keel; midbrain hindbrain boundary; neural plate; and neural tube. Orthologous to human NOTUM (notum, palmitoleoyl-protein carboxylesterase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Flowers et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With notum1a Human Ortholog
No data available
Associated With notum1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004963 Pectinacetylesterase/NOTUM
Domain Details Per Protein
Protein Length Pectinacetylesterase/NOTUM
UniProtKB:C5H5C4 500
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA notum1a-201 (1) Ensembl 2,246 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations