Gene

kcnk3b

ID
ZDB-GENE-120709-43
Name
potassium channel, subfamily K, member 3b
Symbol
kcnk3b Nomenclature History
Previous Names
  • si:ch211-283f6.10 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have potassium ion leak channel activity. Involved in heart contraction. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is expressed in central nervous system and heart. Orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Liang et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcnk3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary pulmonary hypertension Alliance Pulmonary hypertension, primary, 4 615344
Associated With kcnk3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013099 Potassium channel domain
Family IPR003092 Two pore domain potassium channel, TASK family
Family IPR003280 Two pore domain potassium channel
Family IPR005406 Potassium channel subfamily K member 3
Domain Details Per Protein
Protein Length Potassium channel domain Potassium channel subfamily K member 3 Two pore domain potassium channel Two pore domain potassium channel, TASK family
UniProtKB:E7F9D1 383
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kcnk3b-201 (1) Ensembl 1,593 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations