Gene
il21
- ID
- ZDB-GENE-120510-4
- Name
- interleukin 21
- Symbol
- il21 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have cytokine receptor binding activity. Predicted to be involved in immune response. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in asthma and common variable immunodeficiency. Is expressed in several structures, including gill; heart; immune system; liver; and muscle. Orthologous to human IL21 (interleukin 21).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| common variable immunodeficiency 11 | Alliance | ?Immunodeficiency, common variable, 11 | 615767 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Four-helical cytokine-like, core | Interleukin-15/Interleukin-21 family |
|---|---|---|---|
|
UniProtKB:A1YYP5
|
151 | ||
|
UniProtKB:A0A8M2BKC7
|
144 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available