Gene
vegfba
- ID
- ZDB-GENE-120510-3
- Name
- vascular endothelial growth factor Ba
- Symbol
- vegfba Nomenclature History
- Previous Names
-
- si:ch211-245d7.5
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have growth factor activity and heparin binding activity. Involved in cerebellum vasculature development and neuron development. Predicted to localize to membrane. Human ortholog(s) of this gene implicated in myocardial infarction and pulmonary hypertension. Is expressed in brain; head; mid cerebral vein; somite; and trunk. Orthologous to human VEGFB (vascular endothelial growth factor B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Jensen et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR023581 | Platelet-derived growth factor, conserved site |
| Domain | IPR000072 | PDGF/VEGF domain |
| Family | IPR050507 | Platelet-derived/Vascular endothelial growth factor |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
| Homologous_superfamily | IPR036841 | Vascular endothelial growth factor, heparin-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | PDGF/VEGF domain | Platelet-derived growth factor, conserved site | Platelet-derived/Vascular endothelial growth factor | Vascular endothelial growth factor, heparin-binding domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:E7EZR4
|
246 | |||||
|
UniProtKB:A0A8M2B3Z6
|
246 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
vegfba-201
(1)
|
Ensembl | 7,435 nt | ||
| ncRNA |
vegfba-002
(1)
|
Ensembl | 671 nt |
Interactions and Pathways
No data available
Plasmids
No data available