Gene
dchs1a
- ID
- ZDB-GENE-120410-3
- Name
- dachsous cadherin-related 1a
- Symbol
- dchs1a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Orthologous to human DCHS1 (dachsous cadherin-related 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Li-Villarreal et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitral valve prolapse | Alliance | Mitral valve prolapse 2 | 607829 |
| Van Maldergem syndrome 1 | Alliance | Van Maldergem syndrome 1 | 601390 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily |
|---|---|---|---|---|---|
|
UniProtKB:X1WDW2
|
3275 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dchs1a-201
(1)
|
Ensembl | 12,286 nt | ||
| mRNA |
dchs1a-202
(1)
|
Ensembl | 9,970 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance