Gene

kcnj5

ID

ZDB-GENE-120215-97

Name

potassium inwardly rectifying channel subfamily J member 5

Symbol

kcnj5 Nomenclature History

Previous Names

si:ch73-13p12.1

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in potassium ion import across plasma membrane and regulation of monoatomic ion transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in atrium and cardiac ventricle. Human ortholog(s) of this gene implicated in atrial fibrillation; long QT syndrome 13; and primary hyperaldosteronism. Orthologous to human KCNJ5 (potassium inwardly rectifying channel subfamily J member 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnj5 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
long QT syndrome 13	Alliance	Long QT syndrome 13	613485
primary hyperaldosteronism	Alliance	Hyperaldosteronism, familial, type III	613677

Associated With kcnj5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040445	Potassium channel, inwardly rectifying, transmembrane domain
Domain	IPR041647	Inward rectifier potassium channel, C-terminal
Family	IPR016449	Potassium channel, inwardly rectifying, Kir
Homologous_superfamily	IPR013518	Potassium channel, inwardly rectifying, Kir, cytoplasmic
Homologous_superfamily	IPR014756	Immunoglobulin E-set