Gene
acvr2ab
- ID
- ZDB-GENE-120215-23
- Name
- activin A receptor type 2Ab
- Symbol
- acvr2ab Nomenclature History
- Previous Names
-
- si:dkey-264o13.1
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have activin binding activity and activin-activated receptor activity. Predicted to be involved in activin receptor signaling pathway; cellular response to growth factor stimulus; and protein phosphorylation. Predicted to localize to activin receptor complex. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human ACVR2A (activin A receptor type 2A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Preiß et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR000333 | Ser/Thr protein kinase, TGFB receptor |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR045860 | Snake toxin-like superfamily |
Domain Details Per Protein
| Protein | Length | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site | Ser/Thr protein kinase, TGFB receptor | Snake toxin-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BGK0
|
438 | |||||
|
UniProtKB:A0A0R4ISZ9
|
439 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
acvr2ab-201
(1)
|
Ensembl | 1,481 nt |
Interactions and Pathways
No data available
Plasmids
No data available