Gene
kcnq2b
- ID
- ZDB-GENE-120130-1
- Name
- potassium voltage-gated channel, KQT-like subfamily, member 2b
- Symbol
- kcnq2b Nomenclature History
- Previous Names
-
- si:ch211-158n11.6
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable voltage-gated potassium channel activity. Predicted to act upstream of or within potassium ion transmembrane transport and regulation of monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. Is expressed in brain; heart; and inner ear.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| benign neonatal seizures | Alliance | Myokymia | 121200 |
| benign neonatal seizures | Alliance | Seizures, benign neonatal, 1 | 121200 |
| developmental and epileptic encephalopathy 7 | Alliance | Developmental and epileptic encephalopathy 7 | 613720 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ankyrin-G binding site | Ion transport domain | Potassium channel, voltage dependent, KCNQ | Potassium channel, voltage dependent, KCNQ2 | Potassium channel, voltage dependent, KCNQ, C-terminal |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B3S0
|
856 | |||||
|
UniProtKB:E7FEC8
|
840 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnq2-202
(1)
|
Ensembl | 2,523 nt | ||
| mRNA |
kcnq2b-202
(1)
|
Ensembl | 4,819 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance