Gene

rnf213b

ID

ZDB-GENE-110822-1

Name

ring finger protein 213b

Symbol

rnf213b Nomenclature History

Previous Names

mysterin b (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in negative regulation of non-canonical Wnt signaling pathway; sprouting angiogenesis; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleolus. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human RNF213 (ring finger protein 213).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rnf213b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Moyamoya disease	Alliance	{Moyamoya disease 2, susceptibility to}	607151

Associated With rnf213b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR046439	Zinc finger, RZ-type
Family	IPR031248	E3 ubiquitin-protein ligase RNF213
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase