Gene
toporsb
- ID
- ZDB-GENE-110728-3
- Name
- topoisomerase I binding, arginine/serine-rich b
- Symbol
- toporsb Nomenclature History
- Previous Names
-
- wu:fi75f04
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein monoubiquitination and protein polyubiquitination. Human ortholog(s) of this gene implicated in retinitis pigmentosa 31. Orthologous to human TOPORS (TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase).
- Genome Resources
-
- Alliance (1)
- Gene:796087 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Powell et al., 2014
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) Single Cell Expression Atlas (1) Daniocell (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 31 | Alliance | Retinitis pigmentosa 31 | 609923 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger, C3HC4 RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type | Zinc finger, RING-type, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:A0A0R4ICA2
|
939 | ||||
|
UniProtKB:A0A8M1RPD6
|
939 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance