Gene
dscaml1
- ID
- ZDB-GENE-110601-1
- Name
- Down syndrome cell adhesion molecule like 1
- Symbol
- dscaml1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to axon and plasma membrane. Is expressed in ciliary marginal zone; retinal ganglion cell layer; and retinal inner nuclear layer.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| ocular motor apraxia, Cogan type | dscaml1vt1/+; cu2Tg | standard conditions | Ma 马漫修 et al., 2019 |
| ocular motility disease | dscaml1vt1/+; cu2Tg | standard conditions | Ma 马漫修 et al., 2019 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Immunoglobulin V-set domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3ASJ8
|
2144 | |||||||||
|
UniProtKB:A0A8M3AIC6
|
2145 | |||||||||
|
UniProtKB:A0A8M2B3L4
|
2157 | |||||||||
|
UniProtKB:A0A8M2B4A1
|
2158 | |||||||||
|
UniProtKB:A0A0R4IHP4
|
1579 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dscaml1-201
(1)
|
Ensembl | 4,740 nt | ||
| mRNA |
dscaml1-202
(1)
|
Ensembl | 4,188 nt |
Interactions and Pathways
No data available
Plasmids
No data available