Gene
tpo
- ID
- ZDB-GENE-110519-2
- Name
- thyroid peroxidase
- Symbol
- tpo Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Human ortholog(s) of this gene implicated in congenital hypothyroidism and glomerulonephritis. Is expressed in thyroid follicle and thyroid primordium. Orthologous to human TPO (thyroid peroxidase).
- Genome Resources
-
- Alliance (1)
- Gene:569363 (1)
- Note
- None
- Comparative Information
- All Expression Data
- 10 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Fang et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
thyroid dyshormonogenesis 2A | Alliance | Thyroid dyshormonogenesis 2A | 274500 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
congenital hypothyroidism | tpozf3605/zf3605 (TU) | standard conditions | Fang et al., 2022 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Haem peroxidase, animal-type | Haem peroxidase domain superfamily, animal type | Haem peroxidase superfamily |
---|---|---|---|---|
UniProtKB:A0A8M9PP20
|
672 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance