Gene

npc1l1

ID
ZDB-GENE-110510-5
Name
NPC1-like 1
Symbol
npc1l1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Is expressed in liver. Orthologous to human NPC1L1 (NPC1 like intracellular cholesterol transporter 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With npc1l1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Ezetimibe, nonresponse to] 617966
[Low density lipoprotein cholesterol level QTL 7] 617966
Associated With npc1l1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000731 Sterol-sensing domain
Domain IPR032190 Niemann-Pick C1, N-terminal
Domain IPR053956 NPC1, middle luminal domain
Domain IPR053958 HMGCR/SNAP/NPC1-like, sterol-sensing domain
Family IPR003392 Protein patched/dispatched
Family IPR004765 NPC1-like
Domain Details Per Protein
Protein Length HMGCR/SNAP/NPC1-like, sterol-sensing domain Niemann-Pick C1, N-terminal NPC1-like NPC1, middle luminal domain Protein patched/dispatched Sterol-sensing domain
UniProtKB:A0A8M9QJ16 1411
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations