Gene

atp5f1e

ID

ZDB-GENE-110411-22

Name

ATP synthase F1 subunit epsilon

Symbol

atp5f1e Nomenclature History

Previous Names

atp5e
si:ch211-122i22.5

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Predicted to act upstream of or within monoatomic ion transport and proton motive force-driven ATP synthesis. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1). Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Orthologous to human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Mueller et al., 2010

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp5f1e Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
mitochondrial complex V (ATP synthase) deficiency nuclear type 3	Alliance	Mitochondrial complex V (ATP synthase) deficiency, nuclear type 3	614053

Associated With atp5f1e Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR006721	ATP synthase, F1 complex, epsilon subunit, mitochondrial
Homologous_superfamily	IPR036742	ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial