Gene
ghrhrb
- ID
- ZDB-GENE-110127-2
- Name
- growth hormone releasing hormone receptor b
- Symbol
- ghrhrb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled peptide receptor activity and peptide hormone binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in isolated growth hormone deficiency. Orthologous to human GHRHR (growth hormone releasing hormone receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| isolated growth hormone deficiency type IB | Alliance | Growth hormone deficiency, isolated, type IV | 618157 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017983 | GPCR, family 2, secretin-like, conserved site |
| Domain | IPR001879 | GPCR, family 2, extracellular hormone receptor domain |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Family | IPR000832 | GPCR, family 2, secretin-like |
| Family | IPR001771 | GPCR, family 2, vasoactive intestinal peptide receptor 1 |
| Family | IPR050332 | G-protein coupled receptor 2 |
| Homologous_superfamily | IPR036445 | GPCR family 2, extracellular hormone receptor domain superfamily |
Domain Details Per Protein
| Protein | Length | GPCR, family 2, extracellular hormone receptor domain | GPCR family 2, extracellular hormone receptor domain superfamily | GPCR, family 2-like, 7TM | GPCR, family 2, secretin-like | GPCR, family 2, secretin-like, conserved site | GPCR, family 2, vasoactive intestinal peptide receptor 1 | G-protein coupled receptor 2 |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q130
|
529 | |||||||
|
UniProtKB:E7FF79
|
453 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ghrhrb-201
(1)
|
Ensembl | 2,172 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance