Gene

slc34a1a

ID

ZDB-GENE-101006-3

Name

solute carrier family 34 member 1a

Symbol

slc34a1a Nomenclature History

Previous Names

npt2a (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have sodium-dependent phosphate transmembrane transporter activity and sodium:phosphate symporter activity. Predicted to be involved in cellular phosphate ion homeostasis and sodium-dependent phosphate transport. Predicted to localize to apical plasma membrane; brush border; and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Fanconi syndrome; chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis. Orthologous to human SLC34A1 (solute carrier family 34 member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Duan et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc34a1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Fanconi renotubular syndrome 2	Alliance	?Fanconi renotubular syndrome 2	613388
hypophosphatemic nephrolithiasis/osteoporosis 1	Alliance	Nephrolithiasis/osteoporosis, hypophosphatemic, 1	612286
		Hypercalcemia, infantile, 2	616963

Associated With slc34a1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR003841	Sodium-dependent phosphate transport protein

Domain Details Per Protein

Protein	Length	Sodium-dependent phosphate transport protein
UniProtKB:F8W579 InterPro	645

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slc34a1a-201 (1) Ensembl	Ensembl	4,823 nt	Select Tool ZFIN BLAST
mRNA	slc34a1a-202 (1) Ensembl	Ensembl	2,371 nt	Select Tool
mRNA	slc34a1a-203 (1) Ensembl	Ensembl	784 nt	Select Tool
ncRNA	slc34a1a-003 (1) Ensembl	Ensembl	783 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations