Gene

slc34a1a

ID

ZDB-GENE-101006-3

Name

solute carrier family 34 member 1a

Symbol

slc34a1a Nomenclature History

Previous Names

npt2a (1)

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have sodium-dependent phosphate transmembrane transporter activity and sodium:phosphate symporter activity. Predicted to be involved in cellular phosphate ion homeostasis and sodium-dependent phosphate transport. Predicted to localize to apical plasma membrane; brush border; and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Fanconi syndrome; chronic kidney disease; hereditary hypophosphatemic rickets with hypercalciuria; hypophosphatemic nephrolithiasis/osteoporosis 1; and nephrolithiasis. Orthologous to human SLC34A1 (solute carrier family 34 member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Duan et al., 2021
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc34a1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Fanconi renotubular syndrome 2	Alliance	?Fanconi renotubular syndrome 2	613388
hypophosphatemic nephrolithiasis/osteoporosis 1	Alliance	Nephrolithiasis/osteoporosis, hypophosphatemic, 1	612286
		Hypercalcemia, infantile, 2	616963

Associated With slc34a1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR003841	Sodium-dependent phosphate transport protein

Domain Details Per Protein

Protein	Length	Sodium-dependent phosphate transport protein
UniProtKB:F8W579 InterPro	645

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slc34a1a-201 (1) Ensembl	Ensembl	4,823 nt	Select Tool ZFIN BLAST
mRNA	slc34a1a-202 (1) Ensembl	Ensembl	2,371 nt	Select Tool ZFIN BLAST
mRNA	slc34a1a-203 (1) Ensembl	Ensembl	784 nt	Select Tool ZFIN BLAST
ncRNA	slc34a1a-003 (1) Ensembl	Ensembl	783 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations