Gene

kcnn3

ID

ZDB-GENE-100921-56

Name

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Symbol

kcnn3 Nomenclature History

Previous Names

si:dkey-45h18.1

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable calmodulin binding activity and small conductance calcium-activated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within potassium ion transport. Predicted to be located in membrane. Predicted to be active in neuron projection; neuronal cell body; and plasma membrane. Is expressed in atrium and cardiac ventricle. Human ortholog(s) of this gene implicated in paranoid schizophrenia and schizophrenia. Orthologous to human KCNN3 (potassium calcium-activated channel subfamily N member 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnn3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Zimmermann-Laband syndrome 3	618658

Associated With kcnn3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004178	Calmodulin-binding domain
Domain	IPR013099	Potassium channel domain
Family	IPR015449	Potassium channel, calcium-activated, SK
Homologous_superfamily	IPR036122	SK, calmodulin-binding domain superfamily