Gene

kcnc3b

ID

ZDB-GENE-100901-2

Name

potassium voltage-gated channel, Shaw-related subfamily, member 3b

Symbol

kcnc3b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport; protein homooligomerization; and regulation of ion transmembrane transport. Predicted to localize to voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 13. Is expressed in cerebellum. Orthologous to human KCNC3 (potassium voltage-gated channel subfamily C member 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnc3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
spinocerebellar ataxia type 13	Alliance	Spinocerebellar ataxia 13	605259

Associated With kcnc3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000210	BTB/POZ domain
Domain	IPR003131	Potassium channel tetramerisation-type BTB domain
Domain	IPR005821	Ion transport domain
Family	IPR003968	Potassium channel, voltage dependent, Kv
Family	IPR003974	Potassium channel, voltage dependent, Kv3
Homologous_superfamily	IPR011333	SKP1/BTB/POZ domain superfamily
Homologous_superfamily	IPR027359	Voltage-dependent channel domain superfamily

Domain Details Per Protein

Protein	Length	BTB/POZ domain	Ion transport domain	Potassium channel tetramerisation-type BTB domain	Potassium channel, voltage dependent, Kv	Potassium channel, voltage dependent, Kv3	SKP1/BTB/POZ domain superfamily	Voltage-dependent channel domain superfamily
UniProtKB:A0A8M9PLW2 InterPro	654
UniProtKB:A0A8M9P5Y6 InterPro	607
UniProtKB:E1AZA6 InterPro	647
UniProtKB:A0A8M9PG40 InterPro	600
UniProtKB:A0A8M9PG37 InterPro	658
UniProtKB:A0A8M9PU62 InterPro	614

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	kcnc3b-201 (1) Ensembl	Ensembl		1,944 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations