Gene

ephb3b

ID

ZDB-GENE-100811-1

Name

eph receptor B3b

Symbol

ephb3b Nomenclature History

Previous Names

epha3b

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity and transmembrane receptor protein tyrosine kinase activity. Acts upstream of or within embryonic liver development. Predicted to be located in membrane. Is expressed in several structures, including basal plate midbrain region; margin; mesoderm; midbrain; and optic vesicle. Orthologous to human EPHB3 (EPH receptor B3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu779 (26 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ephb3b Human Ortholog

No data available

Associated With ephb3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008266	Tyrosine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Conserved_site	IPR001426	Tyrosine-protein kinase, receptor class V, conserved site
Domain	IPR000719	Protein kinase domain
Domain	IPR001090	Ephrin receptor ligand binding domain
Domain	IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR003961	Fibronectin type III
Domain	IPR020635	Tyrosine-protein kinase, catalytic domain
Domain	IPR027936	Ephrin receptor, transmembrane domain
Domain	IPR034245	Ephrin type-B receptor 3, ligand binding domain
Family	IPR016257	Ephrin receptor type-A /type-B
Family	IPR050449	Ephrin receptor tyrosine kinases
Homologous_superfamily	IPR008979	Galactose-binding-like domain superfamily
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036116	Fibronectin type III superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Ephrin receptor ligand binding domain	Ephrin receptor, transmembrane domain	Ephrin receptor type-A /type-B	Ephrin receptor tyrosine kinases	Ephrin type-B receptor 3, ligand binding domain	Fibronectin type III	Fibronectin type III superfamily	Galactose-binding-like domain superfamily	Growth factor receptor cysteine-rich domain superfamily	Immunoglobulin-like fold	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine-threonine/tyrosine-protein kinase, catalytic domain	Sterile alpha motif domain	Sterile alpha motif/pointed domain superfamily	Tyrosine-protein kinase, active site	Tyrosine-protein kinase, catalytic domain	Tyrosine-protein kinase, receptor class V, conserved site
UniProtKB:A0A8M9PSM0	InterPro	983

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ephb3-201 (1) Ensembl	Ensembl		1,506 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations