Gene
pigu
- ID
- ZDB-GENE-100629-1
- Name
- phosphatidylinositol glycan anchor biosynthesis, class U
- Symbol
- pigu Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Enables GPI-anchor transamidase activity. Acts upstream of or within detection of mechanical stimulus involved in sensory perception of touch and protein localization to cell surface. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of GPI-anchor transamidase complex. Orthologous to human PIGU (phosphatidylinositol glycan anchor biosynthesis class U).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Nakano et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Nakano et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with brain anomalies, seizures, and scoliosis | 618590 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009600 | GPI transamidase subunit PIG-U |
Domain Details Per Protein
| Protein | Length | GPI transamidase subunit PIG-U |
|---|---|---|
|
UniProtKB:D5MQ15
|
435 | |
|
UniProtKB:A0A8M6YYR1
|
367 |
Interactions and Pathways
No data available
Plasmids
No data available