Gene
pigu
- ID
- ZDB-GENE-100629-1
- Name
- phosphatidylinositol glycan anchor biosynthesis, class U
- Symbol
- pigu Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Exhibits GPI-anchor transamidase activity. Involved in detection of mechanical stimulus involved in sensory perception of touch and protein localization to cell surface. Predicted to localize to GPI-anchor transamidase complex. Orthologous to human PIGU (phosphatidylinositol glycan anchor biosynthesis class U).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Nakano et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Nakano et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with brain anomalies, seizures, and scoliosis | 618590 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009600 | GPI transamidase subunit PIG-U |
Domain Details Per Protein
| Protein | Length | GPI transamidase subunit PIG-U |
|---|---|---|
|
UniProtKB:D5MQ15
|
435 | |
|
UniProtKB:A0A8M6YYR1
|
367 |
Interactions and Pathways
No data available
Plasmids
No data available