Gene
git1
- ID
- ZDB-GENE-100408-5
- Name
- G protein-coupled receptor kinase interacting ArfGAP 1
- Symbol
- git1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity and small GTPase binding activity. Acts upstream of or within angiogenesis. Predicted to be active in cytosol; neuron projection; and postsynapse. Is expressed in head. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder. Orthologous to human GIT1 (GIT ArfGAP 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Liu et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001164 | Arf GTPase activating protein |
| Domain | IPR013724 | GIT, Spa2 homology (SHD) domain |
| Domain | IPR022018 | ARF GTPase-activating protein GIT1, C-terminal |
| Domain | IPR032352 | Arf GTPase-activating protein GIT1/2, coiled-coil domain |
| Family | IPR047161 | ARF GTPase-activating protein Git-like |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR037278 | ARFGAP/RecO-like zinc finger |
| Homologous_superfamily | IPR038508 | ArfGAP domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf GTPase activating protein | Arf GTPase-activating protein GIT1/2, coiled-coil domain | ARF GTPase-activating protein GIT1, C-terminal | ARF GTPase-activating protein Git-like | GIT, Spa2 homology (SHD) domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AHJ1
|
667 | |||||||||
|
UniProtKB:A0A0R4IPR8
|
761 | |||||||||
|
UniProtKB:E7FAZ2
|
752 |
Interactions and Pathways
No data available
Plasmids
No data available