Gene
nlgn4xa
- ID
- ZDB-GENE-100309-2
- Name
- neuroligin 4 X-linked a
- Symbol
- nlgn4xa Nomenclature History
- Previous Names
-
- nlgn4a
- nlgn4b (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have neurexin family protein binding activity and signaling receptor activity. Predicted to be involved in several processes, including neuron cell-cell adhesion; synapse assembly; and synaptic vesicle endocytosis. Predicted to localize to cell surface; integral component of plasma membrane; and synapse. Human ortholog(s) of this gene implicated in Asperger syndrome and autistic disorder. Is expressed in several structures, including brain; eye; gonad; spinal cord interneuron; and swim bladder. Orthologous to several human genes including NLGN4X (neuroligin 4 X-linked).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
---|---|---|---|---|---|---|
UniProtKB:R4GE10
|
826 | |||||
UniProtKB:A0A8M9QBU0
|
844 | |||||
UniProtKB:D0EVX4
|
826 |
Interactions and Pathways
No data available
Plasmids
No data available