Gene

phka1b

ID

ZDB-GENE-091204-81

Name

phosphorylase kinase, alpha 1b (muscle)

Symbol

phka1b Nomenclature History

Previous Names

si:dkey-22f5.10

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to contribute to phosphorylase kinase activity. Predicted to be involved in protein phosphorylation. Predicted to localize to phosphorylase kinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease and glycogen storage disease IXd. Orthologous to human PHKA1 (phosphorylase kinase regulatory subunit alpha 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Burkhalter et al., 2019

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With phka1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
glycogen storage disease IXd	Alliance	Muscle glycogenosis	300559

Associated With phka1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR011613	GH15-like domain
Domain	IPR045583	Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain
Family	IPR008734	Phosphorylase kinase alpha/beta subunit
Homologous_superfamily	IPR008928	Six-hairpin glycosidase superfamily
Homologous_superfamily	IPR012341	Six-hairpin glycosidase-like superfamily

Domain Details Per Protein

Protein	Length	GH15-like domain	Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain	Phosphorylase kinase alpha/beta subunit	Six-hairpin glycosidase-like superfamily	Six-hairpin glycosidase superfamily
UniProtKB:A0A8M9PJ81 InterPro	701
UniProtKB:A0A8M9PUY3 InterPro	628
UniProtKB:A0A286YBM7 InterPro	1181
UniProtKB:A0A8M9PRF2 InterPro	600

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	phka1b-201 (1) Ensembl	Ensembl	3,251 nt	Select Tool
mRNA	phka1b-206 (1) Ensembl	Ensembl	3,644 nt	Select Tool ZFIN BLAST
ncRNA	phka1b-002 (1) Ensembl	Ensembl	571 nt	Select Tool
ncRNA	phka1b-004 (1) Ensembl	Ensembl	766 nt	Select Tool
ncRNA	phka1b-005 (1) Ensembl	Ensembl	736 nt	Select Tool
ncRNA	phka1b-006 (1) Ensembl	Ensembl	222 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations