Gene
pdk1
- ID
- ZDB-GENE-091204-402
- Name
- pyruvate dehydrogenase kinase, isozyme 1
- Symbol
- pdk1 Nomenclature History
- Previous Names
-
- si:zfos-979f1.3
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in glucose homeostasis and negative regulation of pyruvate dehydrogenase activity. Predicted to localize to mitochondrion. Orthologous to human PDK1 (pyruvate dehydrogenase kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003594 | Histidine kinase/HSP90-like ATPase domain |
| Domain | IPR005467 | Histidine kinase domain |
| Domain | IPR018955 | Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal |
| Family | IPR039028 | PDK/BCKDK protein kinase |
| Homologous_superfamily | IPR036784 | Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily |
| Homologous_superfamily | IPR036890 | Histidine kinase/HSP90-like ATPase superfamily |
Domain Details Per Protein
| Protein | Length | Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily | Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal | Histidine kinase domain | Histidine kinase/HSP90-like ATPase domain | Histidine kinase/HSP90-like ATPase superfamily | PDK/BCKDK protein kinase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F3U3
|
405 |
Interactions and Pathways
No data available
Plasmids
No data available