Gene
dnaaf3
- ID
- ZDB-GENE-091204-296
- Name
- dynein axonemal assembly factor 3
- Symbol
- dnaaf3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Involved in axonemal dynein complex assembly; cilium movement; and motile cilium assembly. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 2. Is expressed in floor plate spinal cord region; neuromast; peripheral olfactory organ; and pronephros. Orthologous to human DNAAF3 (dynein axonemal assembly factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Mitchison et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 2 | Alliance | Ciliary dyskinesia, primary, 2 | 606763 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Domain of unknown function DUF4470 | Dynein assembly factor 3, axonemal | Dynein assembly factor 3, C-terminal domain |
|---|---|---|---|---|
|
UniProtKB:F1Q7Z7
|
||||
|
UniProtKB:A0A8M9PY38
|
469 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dnaaf3-201
(1)
|
Ensembl | 1,631 nt |
Interactions and Pathways
No data available
Plasmids
No data available