Gene

ank1b

ID

ZDB-GENE-091113-6

Name

ankyrin 1, erythrocytic b

Symbol

ank1b Nomenclature History

Previous Names

si:ch211-263m18.3 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have ion channel binding activity. Predicted to be involved in protein localization to plasma membrane. Predicted to localize to axon initial segment and membrane. Human ortholog(s) of this gene implicated in anemia; hereditary spherocytosis; and hereditary spherocytosis type 1. Orthologous to human ANK1 (ankyrin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ank1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hereditary spherocytosis type 1	Alliance	Spherocytosis, type 1	182900

Associated With ank1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000488	Death domain
Domain	IPR000906	ZU5 domain
Domain	IPR040745	Ankyrin, UPA domain
Family	IPR051165	Multifunctional Ankyrin Repeat Domain-Containing Protein
Homologous_superfamily	IPR011029	Death-like domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Length	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	Ankyrin, UPA domain	Death domain	Death-like domain superfamily	Multifunctional Ankyrin Repeat Domain-Containing Protein	ZU5 domain
UniProtKB:A0A8M9PIW2 InterPro	1930
UniProtKB:A0A8M9PD85 InterPro	1956
UniProtKB:A0A8M9PR23 InterPro	1963
UniProtKB:A0A8M9PUL5 InterPro	1919
UniProtKB:A0A8M9PR28 InterPro	1769
UniProtKB:A0A8M9PDB9 InterPro	2091

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ank1b-201 (1) Ensembl	Ensembl	5,211 nt	Select Tool ZFIN BLAST
mRNA	ank1b-204 (1) Ensembl	Ensembl	5,534 nt	Select Tool
mRNA	ank1b-205 (1) Ensembl	Ensembl	5,304 nt	Select Tool ZFIN BLAST
mRNA	ank1b-206 (1) Ensembl	Ensembl	4,527 nt	Select Tool ZFIN BLAST
mRNA	ank1b-207 (1) Ensembl	Ensembl	3,999 nt	Select Tool ZFIN BLAST
mRNA	ank1b-208 (1) Ensembl	Ensembl	5,157 nt	Select Tool ZFIN BLAST
ncRNA	ank1b-003 (1) Ensembl	Ensembl	746 nt	Select Tool
ncRNA	ank1b-004 (1) Ensembl	Ensembl	695 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations