Gene

pfkpa

ID

ZDB-GENE-091112-22

Name

phosphofructokinase, platelet a

Symbol

pfkpa Nomenclature History

Previous Names

si:ch73-73n3.1

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have several functions, including 6-phosphofructokinase activity; adenyl ribonucleotide binding activity; and fructose-6-phosphate binding activity. Predicted to be involved in several processes, including canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and protein homotetramerization. Predicted to localize to 6-phosphofructokinase complex and membrane. Orthologous to human PFKP (phosphofructokinase, platelet).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Fukuda et al., 2020

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pfkpa Human Ortholog

No data available

Associated With pfkpa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR015912	Phosphofructokinase, conserved site
Domain	IPR000023	Phosphofructokinase domain
Family	IPR009161	ATP-dependent 6-phosphofructokinase, eukaryotic-type
Family	IPR022953	ATP-dependent 6-phosphofructokinase
Family	IPR041914	ATP-dependent 6-phosphofructokinase, vertebrate-type
Homologous_superfamily	IPR035966	Phosphofructokinase superfamily

Domain Details Per Protein

Protein	Length	ATP-dependent 6-phosphofructokinase	ATP-dependent 6-phosphofructokinase, eukaryotic-type	ATP-dependent 6-phosphofructokinase, vertebrate-type	Phosphofructokinase, conserved site	Phosphofructokinase domain	Phosphofructokinase superfamily
UniProtKB:A0A8M3B6I6 InterPro	789
UniProtKB:A0A8M1RMR9 InterPro	787
UniProtKB:A0A8M2B9K3 InterPro	789
UniProtKB:E7FDP2 InterPro	787
UniProtKB:A0A8M2B9C5 InterPro	789
UniProtKB:A0A2R8RK99 InterPro	787
UniProtKB:A0A0R4ITA8 InterPro	787

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pfkpa-201 (1) Ensembl	Ensembl	3,646 nt	Select Tool
mRNA	pfkpa-202 (1) Ensembl	Ensembl	981 nt	Select Tool
mRNA	pfkpa-203 (1) Ensembl	Ensembl	4,228 nt	Select Tool ZFIN BLAST
mRNA	pfkpa-204 (1) Ensembl	Ensembl	4,150 nt	Select Tool ZFIN BLAST
mRNA	pfkpa-205 (1) Ensembl	Ensembl	4,228 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations