Gene
nlgn1
- ID
- ZDB-GENE-090918-1
- Name
- neuroligin 1
- Symbol
- nlgn1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have neurexin family protein binding activity and signaling receptor activity. Involved in sprouting angiogenesis. Predicted to localize to cell surface; integral component of plasma membrane; and synapse. Is expressed in several structures, including brain; cardiovascular system; eye; gonad; and swim bladder. Orthologous to human NLGN1 (neuroligin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism, susceptibility to, 20} | 618830 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Carboxylesterase, type B | Carboxylesterase type B, conserved site | Neuroligin | Neuroligin and Bile salt-activated lipase |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z1K4
|
847 | |||||
|
UniProtKB:D2X2F9
|
867 | |||||
|
UniProtKB:A0A8M6Z363
|
827 | |||||
|
UniProtKB:B6EUL6
|
847 |
Interactions and Pathways
No data available
Plasmids
No data available