Gene
atoh1c
- ID
- ZDB-GENE-090805-1
- Name
- atonal bHLH transcription factor 1c
- Symbol
- atoh1c Nomenclature History
- Previous Names
-
- Zath1c (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have protein dimerization activity and sequence-specific DNA binding activity. Involved in cerebellar granule cell differentiation. Is expressed in brain; midbrain hindbrain boundary neural rod; and midbrain hindbrain boundary neural tube. Orthologous to human ATOH1 (atonal bHLH transcription factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Kidwell et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 89 | Alliance | ?Deafness, autosomal dominant 89 | 620284 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Basic helix-loop-helix transcription factors | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|---|
|
UniProtKB:A0A8M9Q9E7
|
204 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
atoh1c-201
(1)
|
Ensembl | 776 nt |
Interactions and Pathways
No data available
Plasmids
No data available