Gene
cacng2b
- ID
- ZDB-GENE-090624-3
- Name
- calcium channel, voltage-dependent, gamma subunit 2b
- Symbol
- cacng2b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to enable channel regulator activity and voltage-gated calcium channel activity. Predicted to be involved in several processes, including neurotransmitter receptor transport, postsynaptic endosome to lysosome; positive regulation of glutamatergic synaptic transmission; and postsynaptic neurotransmitter receptor diffusion trapping. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in postsynaptic density membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 10. Orthologous to human CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2).
- Genome Resources
-
- Alliance (1)
- Gene:569855 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Roy et al., 2016
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) Single Cell Expression Atlas (1) Daniocell (1)
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Roy et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 10 | Alliance | ?Intellectual developmental disorder, autosomal dominant 10 | 614256 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | PMP-22/EMP/MP20/Claudin | Voltage-dependent calcium channel gamma subunit | Voltage-dependent calcium channel, gamma subunit |
|---|---|---|---|---|
|
UniProtKB:A0A0R4INZ4
|
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance