Gene
cngb3.1
- ID
- ZDB-GENE-090611-1
- Name
- cyclic nucleotide gated channel subunit beta 3, tandem duplicate 1
- Symbol
- cngb3.1 Nomenclature History
- Previous Names
-
- cngb3
- si:ch211-189o17.7
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to act upstream of or within visual perception. Predicted to be part of intracellular cyclic nucleotide activated cation channel complex. Predicted to be active in photoreceptor outer segment and plasma membrane. Human ortholog(s) of this gene implicated in achromatopsia 3 and color blindness. Orthologous to human CNGB3 (cyclic nucleotide gated channel subunit beta 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| achromatopsia 3 | Alliance | Achromatopsia 3 | 262300 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018488 | Cyclic nucleotide-binding, conserved site |
| Domain | IPR000595 | Cyclic nucleotide-binding domain |
| Family | IPR050866 | Cyclic nucleotide-gated cation channel |
| Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
| Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Cyclic nucleotide-binding, conserved site | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Cyclic nucleotide-gated cation channel | RmlC-like jelly roll fold |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PX95
|
787 | |||||
|
UniProtKB:A0A8M3AZ92
|
793 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cngb3.1-201
(1)
|
Ensembl | 2,783 nt | ||
| mRNA |
cngb3.1-202
(1)
|
Ensembl | 2,157 nt |
Interactions and Pathways
No data available
Plasmids
No data available