Gene
igfbp6b
- ID
- ZDB-GENE-090521-2
- Name
- insulin-like growth factor binding protein 6b
- Symbol
- igfbp6b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in obesity. Is expressed in several structures, including eye; gill; heart; liver; and pleuroperitoneal region. Orthologous to human IGFBP6 (insulin like growth factor binding protein 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000716 | Thyroglobulin type-1 |
| Domain | IPR000867 | Insulin-like growth factor-binding protein, IGFBP |
| Family | IPR022321 | Insulin-like growth factor-binding protein family 1-6, chordata |
| Family | IPR022326 | Insulin-like growth factor-binding protein 6 |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR036857 | Thyroglobulin type-1 superfamily |
Domain Details Per Protein
| Protein | Length | Growth factor receptor cysteine-rich domain superfamily | Insulin-like growth factor-binding protein 6 | Insulin-like growth factor-binding protein family 1-6, chordata | Insulin-like growth factor-binding protein, IGFBP | Thyroglobulin type-1 | Thyroglobulin type-1 superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:F6N9E8
|
212 | ||||||
|
UniProtKB:C4MCP1
|
203 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
igfbp6b-201
(1)
|
Ensembl | 1,343 nt |
Interactions and Pathways
No data available
Plasmids
No data available