Gene
chrm1a
- ID
- ZDB-GENE-090410-9
- Name
- cholinergic receptor, muscarinic 1a
- Symbol
- chrm1a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled acetylcholine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to cell junction; integral component of plasma membrane; and postsynaptic membrane. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome; asthma; and myasthenia gravis. Is expressed in eye. Orthologous to human CHRM1 (cholinergic receptor muscarinic 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Nuckels et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Muscarinic acetylcholine receptor family |
|---|---|---|---|---|
|
UniProtKB:A0A8M1Q6V1
|
442 | |||
|
UniProtKB:A0A8M9PN63
|
259 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
chrm1a-201
(1)
|
Ensembl | 1,245 nt | ||
| mRNA |
chrm1a-202
(1)
|
Ensembl | 1,422 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance