Gene
chrm3b
- ID
- ZDB-GENE-090410-5
- Name
- cholinergic receptor, muscarinic 3b
- Symbol
- chrm3b Nomenclature History
- Previous Names
-
- DrM3B (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled acetylcholine receptor activity and G protein-coupled serotonin receptor activity. Predicted to be involved in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway and chemical synaptic transmission. Predicted to localize to dendrite; integral component of plasma membrane; and synapse. Human ortholog(s) of this gene implicated in bladder disease; chronic obstructive pulmonary disease; prune belly syndrome; and pulmonary fibrosis. Is expressed in eye. Orthologous to human CHRM3 (cholinergic receptor muscarinic 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Nuckels et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| prune belly syndrome | Alliance | Prune belly syndrome | 100100 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Muscarinic acetylcholine receptor family |
|---|---|---|---|---|
|
UniProtKB:U3JAM0
|
494 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
chrm3b-201
(1)
|
Ensembl | 1,583 nt |
Interactions and Pathways
No data available
Plasmids
No data available