Gene

ghsrb

ID

ZDB-GENE-090327-1

Name

growth hormone secretagogue receptor b

Symbol

ghsrb Nomenclature History

Previous Names

GHS-R2a (1)
si:dkey-83f6.2

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to have growth hormone secretagogue receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Localizes to perinuclear region of cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in obesity. Is expressed in several structures, including brain; brainstem and spinal white matter; immune system; intestine; and liver. Orthologous to human GHSR (growth hormone secretagogue receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ghsrb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Growth hormone deficiency, isolated partial	615925

Associated With ghsrb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR003905	Growth hormone secretagogue receptor/motilin receptor