Gene

apbb2b

ID
ZDB-GENE-090313-73
Name
amyloid beta (A4) precursor protein-binding, family B, member 2b
Symbol
apbb2b Nomenclature History
Previous Names
  • apbb2
  • si:ch211-201g8.2
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have amyloid-beta binding activity and transcription factor binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease and cognitive disorder. Orthologous to human APBB2 (amyloid beta precursor protein binding family B member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Anderson et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With apbb2b Human Ortholog
No data available
Associated With apbb2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001202 WW domain
Domain IPR006020 PTB/PI domain
Family IPR039576 Amyloid beta precursor protein binding family B member 1/2/3
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036020 WW domain superfamily
Domain Details Per Protein
Protein Length Amyloid beta precursor protein binding family B member 1/2/3 PH-like domain superfamily PTB/PI domain WW domain WW domain superfamily
UniProtKB:A0A8M3AZH4 889
UniProtKB:A0A8M9PIS6 890
UniProtKB:A0A8N7TDH9 890
UniProtKB:A0A8M2BFP7 211
UniProtKB:A0A8M9PKH7 874
UniProtKB:A0A8M2BFP9 892
UniProtKB:A0A8M3B8B5 590
UniProtKB:A0A8M6YY48 891
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA apbb2b-201 (1) Ensembl 3,326 nt
mRNA apbb2b-202 (1) Ensembl 2,097 nt
mRNA apbb2b-203 (1) Ensembl 479 nt
ncRNA apbb2b-002 (1) Ensembl 527 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations