Gene
cpe
- ID
- ZDB-GENE-090313-68
- Name
- carboxypeptidase E
- Symbol
- cpe Nomenclature History
- Previous Names
-
- si:ch211-198g9.2
- zgc:85981
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process and protein processing. Predicted to act upstream of or within proteolysis. Predicted to be active in extracellular space. Is expressed in hypural; posterior pancreatic bud; and retina. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CPE (carboxypeptidase E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Klingbeil et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| BDV syndrome | 619326 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Carboxypeptidase E, carboxypeptidase domain | Carboxypeptidase-like, regulatory domain superfamily | Peptidase M14, carboxypeptidase A | Peptidase M14 domain-containing protein |
|---|---|---|---|---|---|
|
UniProtKB:Q6NSM5
|
Interactions and Pathways
No data available
Plasmids
No data available